Hypertension risk in Psoriasis Patients
Recent medical journal reports published on the JAMA Dermatology publications in October 2014 has shown that there is a positive correlation between the incidence of moderate to severe Psoriasis, and uncontrolled hypertension. In fact, the more severe the Psoriasis symptoms are, the greater the risk for uncontrolled hypertension.
This was a result of a study of 1322 patients who were suffering from both conditions, as compared to 11977 control patients who had hypertension but not psoriasis. Both groups had the same likelihood of taking anti-hypertensive medication.
In another study by Perelman School of Medicine at the University of Pennsylvania in Philadelphia, increased heart disease risk is believed to be aligned to the increased systemic inflammation that cause Psoriasis, and even other types of conditions such as rheumatoid arthritis. These inflammations that occur on throughout the body also has been thought to relate to the premature build up of plaque in the arteries.
While Psoriasis affects 7.5 million Americans, between 10% and 20% of these patients also experience inflammatory arthritis at the same time. Both of these conditions are caused by a malfunction in the immune system. More than 50% of those who are suffering from Psoriatic Arthritis have also been prescribed disease-modifying anti-rheumatic drugs (DMARD).
One of the unknown areas is whether immunosuppressive medications are able to also reduce the risk of heart disease. Concurrently, patients with severe forms of inflammatory skin disease are also seeking a lot of treatment. With this, studies have not found whether the increased risk of heart disease could be related to the immune system, or to the treatment that they have received.
Doctors have mentioned that this finding is not new and the positive correlation has been known for quite some time. The difference now is that, further studies now have utilized a larger sample size and thus firms up the findings or conclusion of this occurrence thus far.
In another study by the British Journal of Dermatology on the increase incidence of Psoriasis on patients with Coronary Artery Disease (CAD), it has been found that these 8% of these CAD patients suffered from psoriasis, as compared to 3.4% of patients of the same age and gender who are without psoriasis.
With these findings, patients who have psoriatic arthritis, rheumatoid arthritis and moderate to severe psoriasis should be made aware of this heightened risk and take the necessary precautions.